Woman wearing a BRAIN.ONE sensor beside a readout of stress level, heart rate variability, attention score and brain waves
Research
Independent ethics review

BRAIN.ONE's research is approved by an independent ethics board.

Every study runs under independent ethics review, with informed consent and documented data handling. The claim we defend on this page is narrow: brain health can be measured from home, weekly, well enough to tell whether a protocol is working for you.

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Evidence pillars

Four principles behind every protocol

01

Several changes at once

The 2024 Lancet Commission identified 14 modifiable risk factors linked to up to 45% of dementia cases. Most sit in different domains, so our protocols move sleep, movement, nutrition, stress and cognitive load in the same week rather than one at a time.

02

Measured continuously, from home

A 60-second face scan and short digital tasks capture nervous-system and thinking signals from home. Weekly readings make small effects visible; an annual clinic visit does not.

03

A score you can see inside

The Brain Score resolves into five dimensions, not one opaque number. Every change in the score traces back to a specific input — so it can be checked, not just trusted.

04

Behavior change that sticks

An intervention nobody completes has no effect size. Protocols are built as 15 to 30 minute daily actions over 12 weeks, the dose adherence research supports.

What we measure

Signals tracked every week

Six signals, taken weekly with the same instruments, so each reading is compared against your own history rather than a population average.

  • Processing speed and attention
  • Working memory and recall
  • Executive function
  • Nervous-system balance (HRV)
  • Sleep regularity and recovery
  • Stress and resilience load
Method

How we test whether a protocol worked

  1. 01

    Baseline

    One session establishes your five-part profile: thinking tasks, face-scan nervous-system signals and validated questionnaires. Everything later is compared against it.

  2. 02

    Protocol assignment

    Your profile maps to a track — general longevity, dementia risk, head-injury support or nervous-system recovery — with a stated target for each week.

  3. 03

    Weekly re-measurement

    The same instruments repeat weekly. You are the control group: the comparison is your own trend line, not a population average.

  4. 04

    Review and adaptation

    If a dimension does not move, the protocol changes. Advisors review performance in aggregate; a protocol that fails to move its target marker is retired.

Oversight

Reviewed by our scientific and medical advisors

Protocols, scoring, and measurement methods are reviewed by the BRAIN.ONE team before release. BRAIN.ONE is not a medical device and does not provide medical advice or diagnosis.

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