New — share protocols with your clinician. Learn about clinician sharing

Your brain has a healthspan.
Now you can measure it.

Blood biomarkers, cognition, wearables, and digital biomarkers — one evolving picture of brain health. Entirely remote, 15–30 minutes a day.

Start with a baseline
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Starting is easy

01

60-second face scan

Scan at home or wherever you are

02

Baseline explained

By AI trained on 500+ studies.

03

Your protocol

Act daily. Re-measure.

ADDITIONAL DIAGNOSTICS

Go deeper when you want more signal

Optional tests you can add to a baseline. Each one adds a layer to your picture, and every result is read alongside your daily measures.

BRAIN.ONE baseline kit box held in two hands

Blood brain panel

Inflammation, metabolic and vascular markers tied to brain health, plus vitamin and hormone levels that shape how you think and sleep.

Genomic profile

A one-time read of inherited factors — including APOE — that influence long-term risk and how you respond to certain habits.

Epigenetic age

A biological age estimate you can re-test over time to see whether your pace of aging is slowing.

EEG assessment

A clinical-grade recording of brain rhythms at rest and under load, giving a detailed picture of attention and recovery.

Sleep study

Multi-night measurement of sleep stages, breathing and heart rate to find what is quietly limiting your recovery.

Cognitive testing

Validated tasks for memory, processing speed and focus, repeated on a schedule so change is measurable, not felt.

Availability varies by location. Tests are ordered and reviewed by licensed clinicians.

Every cycle raises the baseline

Measure. Interpret. Act. Re-measure.

01 · MEASURE

Build your baseline

Blood + cognition + wearables + digital biomarkers + optional EEG.

02 · UNDERSTAND

See what changed

AI connects patterns across systems and tracks change over time.

03 · ACT

Follow your protocol

Personalized protocols for sleep, movement, nutrition, stress and cognition.

04 · RE-MEASURE

Raise the baseline

Repeat key tests and continuously adapt the plan.

Start with a baselineSee how it works
Featured protocol

Malik Jackson TBI Support Protocol

Football · Defensive Tackle · United States

Recovery from repeated head impact — built around deep sleep, inflammation control and steady cognitive load.

Malik Jackson, football defensive tackle, following the TBI Support Protocol
“You do not out-train impact. You recover from it, every single day.”
View the full day
A day on the protocol
  1. 6:30 AM
    Morning
    Light, water, cellular support
    Ten minutes of outdoor light before any screen, 20oz of water, then the metabolic formulation on an empty stomach.
    Anchors the circadian rhythm and supports steady cerebral energy through the morning.
    1 serving Metabolic Optimization
  2. 8:00 AM
    Morning
    Cognitive block
    A single focused work block, 45 minutes on, 15 minutes off. No task-switching, no notifications.
    Rebuilds sustained attention without pushing past the fatigue threshold.
    —
  3. 11:00 AM
    Training
    Low-impact conditioning
    Bike, pool or sled — nothing with head movement or impact. Heart rate capped at conversational effort.
    Drives cerebral blood flow without provoking symptoms.
    —
  4. 1:00 PM
    Recovery
    Inflammation control
    Taken with the largest meal of the day.
    Supports the resolution of systemic and neuro-inflammation after load.
    1 serving InflammX
  5. 4:00 PM
    Recovery
    Vestibular and vision work
    Ten minutes of gaze stabilisation and balance drills, stopping at the first sign of symptoms.
    Retrains the vestibulo-ocular system commonly disrupted after head injury.
    —
  6. 9:00 PM
    Sleep
    Wind-down and deep sleep
    Screens down, room cold and dark, formulation 30 minutes before bed. Same lights-out time every night.
    Deep sleep is where glymphatic clearance happens — the single highest-leverage block in the protocol.
    1 serving Deep Sleep
See all protocols

The new standard for brain health

Fitness for a new, discerning generation

USA TodayOptimize your brain with micro habits
Maya R., BRAIN.ONE member
“I finally understand my own focus.”
Maya R.
Daniel K., BRAIN.ONE member
“BRAIN.ONE helped me fix my sleep for good.”
Daniel K.
LA WeeklyPersonalized brain fitness, no longer just for the elite
Ines A., BRAIN.ONE member
“Small habits, huge difference.”
Ines A.
VentureBeatAI-powered brain fitness protocolsThe Aspen TimesAspen start-up looks to revolutionize health and wellness
Jonas T., BRAIN.ONE member
“I deeply believe in this mission.”
Jonas T.
The team

Built by experts in brain health

Researchers, scientists and clinicians building measurable brain healthspan.

Thoryn Stephens
Thoryn Stephens
CEO
Dr. Galen Buckwalter
Dr. Galen Buckwalter
AI Advisory
Dr. Shera Raisen, MD
Dr. Shera Raisen, MD
Medical Advisory
Dr. Barbara Krutchkoff
Dr. Barbara Krutchkoff
Scientific Advisory

One way to start.

Every path begins with a measurement. The 12-week program is the first structured experience inside a much larger brain health intelligence platform.

Starts at $399 for your baseline and blood biomarkers.
$2,499 for the full 12-week Brain Longevity Program.

★★★★★

“The experience, the price, and the human review are all phenomenal.”

★★★★★

“The most complete picture of my brain I’ve ever had. Thrilled to know what to do next.”

★★★★★

“Best money I’ve spent on my health.”

Frequently asked questions

A baseline assessment, a 60-second face scan, and your first personalized protocol — a short daily set of microhabits built from your own results, delivered remotely with weekly check-ins.

Sharper focus. Steadier mood.
A brain built to last.

Start with a baselineWhat we measure